Dr. Greicius is the Iqbal Farrukh and Asad Jamal Professor in the Department of Neurology and Neurological Sciences at the Stanford University School of Medicine. He majored in French at Amherst College prior to attending medical school at the Columbia University College of Physicians and Surgeons. He then did his neurology residency at the Harvard Partners program, and completed a behavioral neurology fellowship at UCSF. He first came to Stanford in 2000 as a postdoctoral fellow and joined the faculty in 2007.
Dr. Greicius is the founding director of the Stanford Center for Memory Disorders and leads a research team studying the genetics of Alzheimer’s disease.
Current efforts in the Greicius lab are focused on identifying novel genetic variants in two groups of subjects: healthy older people carrying the high risk APOE4 genetic variant and early age-at-onset Alzheimer’s patients who do not carry the high risk APOE4 genetic variant. The goal is to identify rare but powerful genetic mutations that either protect against or cause Alzheimer’s disease, respectively in these two groups. These genetic variants will then be characterized in detail to understand how they impact disease risk and how their related molecular pathways can be targeted for novel drug development.
Most recently, the lab has delved into long-read sequencing to identify large structural variants that are often missed with standard next-generation sequencing.
As a former French major, passable Francophone, and longtime Francophile, he is doubly enthusiastic about being on the VBHI scientific advisory board.
